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1985•Acta Pathologica Microbiologica Scandinavica Series A PathologyRequires access

KERATIN PROTEINS IN THE EPITHELIUM OF THE UTERINE CERVIX

Christence Stubbe Teglbjærg, Bodil Norrild, Erik Dabelsteen

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Abstract

Keratin proteins in human cervical squamous epithelium were investigated by the immunofluorescence technique, using the monoclonal keratin antibodies AE1 and AE2. Although the exocervic is covered by a non-keratinizing, histologically homogenous, squamous epithelium, different staining patterns were found within a single histological section. This indicates a regional variation in the maturation pattern of stratified exocervical epithelium. Detection of morphological versus biochemical keratinization in the diagnosis of pathological cervical conditions is discussed.

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Keratin proteins in human cervical squamous epithelium were investigated by the immunofluorescence technique, using the monoclonal keratin antibodies AE1 and AE2. Although the exocervic is covered by a non-keratinizing, histologically homogenous, squamous epithelium, different staining patterns were found within a single histological section. This indicates a regional variation in the maturation pattern of stratified exocervical epithelium. Detection of morphological versus biochemical keratinization in the diagnosis of pathological cervical conditions is discussed.

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Available abstract

Keratin proteins in human cervical squamous epithelium were investigated by the immunofluorescence technique, using the monoclonal keratin antibodies AE1 and AE2. Although the exocervic is covered by a non-keratinizing, histologically homogenous, squamous epithelium, different staining patterns were found within a single histological section. This indicates a regional variation in the maturation pattern of stratified exocervical epithelium. Detection of morphological versus biochemical keratinization in the diagnosis of pathological cervical conditions is discussed.

Key concepts: Keratin, Epithelium, Uterine cervix, Cervix, Biology, Andrology, Medicine, Pathology

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