Quantitative Biochemical Changes in Single Nerve Cells of the Vestibular System at Different Functional States
Chr. Blomstrand, O. Hallén, Anders Hamberger, Jan Jarlstedt
Abstract
Chr. Blomstrand, O. Hallén, Anders Hamberger, Jan Jarlstedt
Abstract
As parameters of functional level using quantitative methods total amount of RNA and succinoocidase activity have been measured in single dissected out cells from the lateral vestibular nucleus and from different areas of cerebellar cortex in rabbit. Bilateral samples have been analyzed after section of the vestibular nerve on the right side, after unspecific vestibular stimulation and after repeated calorization with warm and cold water. The results show it is possible to demonstrate dysbalance in the vestibular system in biochemical terms and that a change of the functional state on one side influences the functional state of the same structures on the other side.
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As parameters of functional level using quantitative methods total amount of RNA and succinoocidase activity have been measured in single dissected out cells from the lateral vestibular nucleus and from different areas of cerebellar cortex in rabbit. Bilateral samples have been analyzed after section of the vestibular nerve on the right side, after unspecific vestibular stimulation and after repeated calorization with warm and cold water. The results show it is possible to demonstrate dysbalance in the vestibular system in biochemical terms and that a change of the functional state on one side influences the functional state of the same structures on the other side.
Key concepts: Vestibular system, Vestibular nerve, Vestibular nuclei, Cerebellar cortex, Neuroscience, Stimulation, Anatomy, Nerve cells