THE MANNICH REACTION OF DIETHYLPHOSPHONOACETIC ACID PART II.1A NEW ROUTE TO 1-(N-ALKYLAMINO)METHYLVINYLPHOSPHONATES
Henryk Krawczyk
Abstract
Henryk Krawczyk
Abstract
The Mannich reaction of diethylphosphonoacetic acid (1) with paraformaldehyde and primary aliphatic amines provides a short and efficient approach to vinylphosphonates 5.
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The Mannich reaction of diethylphosphonoacetic acid (1) with paraformaldehyde and primary aliphatic amines provides a short and efficient approach to vinylphosphonates 5.
Key concepts: Paraformaldehyde, Mannich reaction, Primary (astronomy), Mannich base, Chemistry, Organic chemistry, Combinatorial chemistry, Catalysis