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Metabolism of Trichloroethylene in the Bovine.

Takashi Seto, M.O. Schultze

Open publisher page 3 citations

Abstract

Following the oral administration of 3 to 12 g of trichloroethylene to calves weighing about 100 lb, about 1% of this compound was excreted in the urine as trichloroacetic acid and from 13 to 25% as trichloro-ethanol (free and combined). Only traces of trichloroethylene were excreted in the urine. No trichloroacetaldehyde could be demonstrated in the urine with the method used. Some of the metabolic products of trichloroethylene in the bovine are the same as those produced by man and dogs.

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What this paper is about

Following the oral administration of 3 to 12 g of trichloroethylene to calves weighing about 100 lb, about 1% of this compound was excreted in the urine as trichloroacetic acid and from 13 to 25% as trichloro-ethanol (free and combined). Only traces of trichloroethylene were excreted in the urine. No trichloroacetaldehyde could be demonstrated in the urine with the method used. Some of the metabolic products of trichloroethylene in the bovine are the same as those produced by man and dogs.

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Available abstract

Following the oral administration of 3 to 12 g of trichloroethylene to calves weighing about 100 lb, about 1% of this compound was excreted in the urine as trichloroacetic acid and from 13 to 25% as trichloro-ethanol (free and combined). Only traces of trichloroethylene were excreted in the urine. No trichloroacetaldehyde could be demonstrated in the urine with the method used. Some of the metabolic products of trichloroethylene in the bovine are the same as those produced by man and dogs.

Key concepts: Trichloroethylene, Trichloroacetic acid, Urine, Chemistry, Chromatography, Ethanol, Metabolism, Biochemistry

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