1994•PubMedRequires access
Coadministration of fluvoxamine increases serum concentrations of haloperidol.
David G. Daniel, Carla Randolph, George E. Jaskiw, Susan E. Handel, Tracy Ann Williams, Anissa Abi‐Dargham, Susan E. Shoaf, M.F. Egan, Ahmed Elkashef, S Liboff
Open publisher page 94 citations
Abstract
Four patients with chronic schizophrenia were treated with a combination of fluvoxamine, haloperidol, and benztropine. The combination significantly impaired performance on tests of delayed recall memory and attentional function. Haloperidol concentrations in serum were monitored in three patients and were robustly elevated by fluvoxamine.