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2012•ImmunityOpen access

Ubiquitin-Induced Oligomerization of the RNA Sensors RIG-I and MDA5 Activates Antiviral Innate Immune Response

Xiaomo Jiang, Lisa N. Kinch, Chad A. Brautigam, Xiang Chen, Fenghe Du, Nick V. Grishin, Zhijian J. Chen

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Key concepts: MDA5, IRF3, RIG-I, Ubiquitin, Biology, Cell biology, Innate immune system, RNA

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