1996•International Journal of OncologyRequires access

Clinicopathologic comparison of hepatitis B virus-related and hepatitis C virus-related hepatocellular carcinoma

T Takazawa, O Nakashima, J Sueda, M. Tanaka, M Kojiro

Abstract

137 cases of hepatocellular carcinoma associated with cirrhosis that had undergone resection between 1991-95 have been analyzed. One hundred and three had hepatitis C (positive for anti HCV alone) and 34 hepatitis B (positive for HBsAg alone). The hepatitis C cases were older and were associated with more severe cirrhosis. The tumors from hepatitis B cases were on average larger and histologically less-differentiated, and were more likely to occur in the background of macronodular cirrhosis than hepatitis C cases.

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Key concepts: Hepatocellular carcinoma, Cirrhosis, HBsAg, Hepatitis B virus, Hepatitis, Hepatitis B, Medicine, Gastroenterology