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DOPAMINE INFUSION ACUTELY INHIBITS THE TSH AND PROLACTIN RESPONSE TO TRH

G. S. Besses, G N Burrow, Stephen W. Spaulding, RICHARD K. DONABEDIAN, T. Pechinski

Open publisher page 199 citations

Abstract

Ten normal males were given 100 mug TRH, and blood samples obtained for serum TSH and serum prolactin. After a period of at least one week, the TRH test was repeated while the patients were receiving a dopamine infusion. Both the TSH and prolactin response to TRH were inhibited by dopamine. Dopaminergic neurons may act through the pituitary-portal system to play a role in the regulation of TSH and prolactin secretion.

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What this paper is about

Ten normal males were given 100 mug TRH, and blood samples obtained for serum TSH and serum prolactin. After a period of at least one week, the TRH test was repeated while the patients were receiving a dopamine infusion. Both the TSH and prolactin response to TRH were inhibited by dopamine. Dopaminergic neurons may act through the pituitary-portal system to play a role in the regulation of TSH and prolactin secretion.

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OpenAlex reports 199 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Ten normal males were given 100 mug TRH, and blood samples obtained for serum TSH and serum prolactin. After a period of at least one week, the TRH test was repeated while the patients were receiving a dopamine infusion. Both the TSH and prolactin response to TRH were inhibited by dopamine. Dopaminergic neurons may act through the pituitary-portal system to play a role in the regulation of TSH and prolactin secretion.

Key concepts: Prolactin, Endocrinology, Internal medicine, Dopaminergic, Dopamine, TRH stimulation test, Thyrotropin-releasing hormone, Medicine

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DOPAMINE INFUSION ACUTELY INHIBITS THE TSH AND PROLACTIN RESPONSE TO TRH — Research Paper | ScholarLens