2011•Journal of Medicine in the TropicsRequires access
Lipid Profile of Patients with Liver Cirrhosis in Jos, Nigeria
EN Okeke, CA Daniyam, Maxwell Oluwole Akanbi, SO Ugoya, Emmanuel I. Agaba
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Abstract
Background: Liver cirrhosis is a chronic inflammatory condition associated lipid abnormalities. There are no studies documenting lipid levels among patients with liver cirrhosis in northern Nigeria.Methodology: Seventy four consecutive patients with liver cirrhosis seen at the Jos University Teaching Hospital and 88 apparently healthy controls had lipid levels estimated in the fasting state.Results: The median serum triglyceride levels were similar in both patients and controls (2.6 mmol/L versus 2.6 mmol/L, ÷2 0.09, P=0.7). The median LDL were also similar being 2.3 mmol/L and 1.9 mmol/L respectively, ÷2 =2.75 p= 0.09. However, the median total cholesterol and HDL cholesterol levels were significantly higher in the controls compared to the 2 study subjects (4.2 mmol/L vs. 3.6 mmol/L; X = 10.1; P=0.0001, and 1.1 mmol/L vs. 0.9 mmol/L; ÷2 = 21.7l, P