2007•Cancer CellOpen access
Defining the Role of mTOR in Cancer
David A. Guertin, David M. Sabatini
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David A. Guertin, David M. Sabatini
Abstract
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Key concepts: PI3K/AKT/mTOR pathway, Discovery and development of mTOR inhibitors, RPTOR, Effector, mTORC2, Mechanistic target of rapamycin, Cancer, Cancer research