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Primary low‐grade B‐cell lymphoma of the conjunctiva: a mucosa‐associated lymphoid tissue type lymphoma

Andrew Charles Wotherspoon, Tim C. Diss, Lingxiao Pan, Christoph Schmid, Malcolm G. Kerr-Muir, S. Hardman Lea, P G Isaacson, HARDMAN LEA S, ISAACSON P. G

Open publisher page 99 citations

Abstract

We describe the clinical presentation, morphology, immunophenotypic features and molecular biology of seven cases of conjunctival lymphoid infiltration. In five cases there was either immunophenotypic or molecular evidence of B-cell lymphoma. Each of these cases showed the morphological, immunophenotypic and molecular feature of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type. The findings suggest that most conjunctival lymphomas are of this type and explains their uniformly favourable prognosis.

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Available abstract

Key concepts: Lymphoma, Pathology, Lymphatic system, Mucosa-associated lymphoid tissue, Conjunctiva, Immunophenotyping, MALT lymphoma, Infiltration (HVAC)