1996•The Journal of AntibioticsOpen access
GERI-155, a New Macrolide Antibiotic Related to Chalcomycin.
Shin-Duk Kim, In‐Ja Ryoo, Chang‐Jin Kim, Won‐Gon Kim, Jong-Pyung Kim, Jae‐Yang Kong, Hiroyuki Koshino, Masakazu Uramoto, Ick‐Dong Yoo
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Abstract
In the course of screening new antibiotics from soil microorganisms, we have isolated GERI-155 as a new naturally occurring antibiotic.GERI-155 shows antimicrobial activities against Gram-positive bacteria.In addition, two known compounds, chalcomycin1?2) and aldgamycin E3'4), were also detected in the same culture broth.This communication describes the isolation, physico-chemical properties, structure and antibacterial activity of GERI-155 (Fig. 1).The producing organism, Streptomyces sp.GERI-1 55, was isolated from a soil sample collected in Cheolwongun, Kangwon-do, Korea, and deposited at the Korea
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