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2005•Applied Physics LettersRequires access

Detection of single magnetic bead for biological applications using an InAs quantum-well micro-Hall sensor

G. Mihajlović, Peng Xiong, Stephan von Molnár, Keita Ohtani, Hideo Ohno, Mark N. Field, Gerard Sullivan

Open publisher page 75 citations

Abstract

Room-temperature detection of a single commercial superparamagnetic bead (1.2μm in diameter) suitable for biological applications has been realized using an InAs quantum-well micro-Hall sensor. The detection was demonstrated using phase-sensitive detection on a single Hall cross as well as in a Hall gradiometry setup. The high signal to noise ratio, obtained in both configurations, promises detection of single nanometer-size particles by further miniaturization of the device to submicron dimensions.

About this research paper

What this paper is about

Room-temperature detection of a single commercial superparamagnetic bead (1.2μm in diameter) suitable for biological applications has been realized using an InAs quantum-well micro-Hall sensor. The detection was demonstrated using phase-sensitive detection on a single Hall cross as well as in a Hall gradiometry setup. The high signal to noise ratio, obtained in both configurations, promises detection of single nanometer-size particles by further miniaturization of the device to submicron dimensions.

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OpenAlex reports 75 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Room-temperature detection of a single commercial superparamagnetic bead (1.2μm in diameter) suitable for biological applications has been realized using an InAs quantum-well micro-Hall sensor. The detection was demonstrated using phase-sensitive detection on a single Hall cross as well as in a Hall gradiometry setup. The high signal to noise ratio, obtained in both configurations, promises detection of single nanometer-size particles by further miniaturization of the device to submicron dimensions.

Key concepts: Miniaturization, Hall effect sensor, Superparamagnetism, Quantum Hall effect, Bead, Hall effect, Materials science, Magnetic bead

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