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1974•Scandinavian Journal of HaematologyRequires access

Blood Lymphocytes in Hodgkin's Disease Lymphocytopenia Related to Stages and Histological Groups

Hans Erik Heier, Trine Normann

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Abstract

The peripheral blood lymphocyte counts of 78 untreated Hodgkin patients have been reviewed and related to stages and histological groups. Sixty‐two of the patient were staged by diagnostic laparatomy, while the other 16 had evident stage IV disease. Seventy‐eight per cent of the lymphocytopenic patients had stage III or IV disease. Lymphocyte depletion histology was associated with a high incidence of lymphocyte penia, but this may be due to accumulation of stage IV patients in this histological group. It is concluded that blood lymphocytopenia in Hodgkin's disease is mainly a feature of a far advanced stage in the disease.

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What this paper is about

The peripheral blood lymphocyte counts of 78 untreated Hodgkin patients have been reviewed and related to stages and histological groups. Sixty‐two of the patient were staged by diagnostic laparatomy, while the other 16 had evident stage IV disease. Seventy‐eight per cent of the lymphocytopenic patients had stage III or IV disease. Lymphocyte depletion histology was associated with a high incidence of lymphocyte penia, but this may be due to accumulation of stage IV patients in this histological group. It is concluded that blood lymphocytopenia in Hodgkin's disease is mainly a feature of a far advanced stage in the disease.

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Available abstract

The peripheral blood lymphocyte counts of 78 untreated Hodgkin patients have been reviewed and related to stages and histological groups. Sixty‐two of the patient were staged by diagnostic laparatomy, while the other 16 had evident stage IV disease. Seventy‐eight per cent of the lymphocytopenic patients had stage III or IV disease. Lymphocyte depletion histology was associated with a high incidence of lymphocyte penia, but this may be due to accumulation of stage IV patients in this histological group. It is concluded that blood lymphocytopenia in Hodgkin's disease is mainly a feature of a far advanced stage in the disease.

Key concepts: Lymphocytopenia, Stage (stratigraphy), Disease, Medicine, Lymphocyte, Histology, Pathology, Incidence (geometry)

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