2014Annals of Internal MedicineRequires access

Edoxaban was noninferior to warfarin for preventing recurrent venous thromboembolism, with less bleeding

Stephan D. Thomé

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Abstract

ACP Journal Club21 January 2014Edoxaban was noninferior to warfarin for preventing recurrent venous thromboembolism, with less bleedingStephan Thomé, MDStephan Thomé, MDMayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-160-2-201401210-02004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationHokusai-VTE Investigators. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013;369:1406-15. https://pubmed.ncbi.nlm.nih.gov/23991658Clinical Impact RatingsGIM/FP/GP: Cardiology: Hematology: References1 Eikelboom JW, Connolly SJ, Brueckmann M, et al; RE-ALIGN Investigators. Dabigatran versus warfarin in patients with mechanical heart valves. N Engl J Med. 2013;369:1206-14. [PMID: 23991661] Google Scholar2 EINSTEIN Investigators, Bauersachs R, Berkowitz SD, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Eng J Med. 2010;363;2499-510. [PMID: 21128814] Google Scholar3 Agnelli G, Buller HR, Cohen A; AMPLIFY Investigators. Oral apixaban for the treatment of acute venous thromboembolism. N Eng J Med. 2013;369;799-808. [PMID: 23808982] Google Scholar Author, Article, and Disclosure InformationAuthors: Stephan Thomé, MDAffiliations: Mayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)This article was published at Annals.org on 7 January 2014. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdentification of potential drug targets based on a computational biology algorithm for venous thromboembolism 21 January 2014Volume 160, Issue 2 Page: JC4 Keywords Cancer treatment Creatinine Deep vein thrombosis Hazard ratio Hemorrhage Heparin Pulmonary embolism Safety Venous thromboembolism Vitamin K ePublished: 21 January 2014 Issue Published: 21 January 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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ACP Journal Club21 January 2014Edoxaban was noninferior to warfarin for preventing recurrent venous thromboembolism, with less bleedingStephan Thomé, MDStephan Thomé, MDMayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-160-2-201401210-02004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationHokusai-VTE Investigators. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013;369:1406-15. https://pubmed.ncbi.nlm.nih.gov/23991658Clinical Impact RatingsGIM/FP/GP: Cardiology: Hematology: References1 Eikelboom JW, Connolly SJ, Brueckmann M, et al; RE-ALIGN Investigators. Dabigatran versus warfarin in patients with mechanical heart valves. N Engl J Med. 2013;369:1206-14. [PMID: 23991661] Google Scholar2 EINSTEIN Investigators, Bauersachs R, Berkowitz SD, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Eng J Med. 2010;363;2499-510. [PMID: 21128814] Google Scholar3 Agnelli G, Buller HR, Cohen A; AMPLIFY Investigators. Oral apixaban for the treatment of acute venous thromboembolism. N Eng J Med. 2013;369;799-808. [PMID: 23808982] Google Scholar Author, Article, and Disclosure InformationAuthors: Stephan Thomé, MDAffiliations: Mayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)This article was published at Annals.org on 7 January 2014. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdentification of potential drug targets based on a computational biology algorithm for venous thromboembolism 21 January 2014Volume 160, Issue 2 Page: JC4 Keywords Cancer treatment Creatinine Deep vein thrombosis Hazard ratio Hemorrhage Heparin Pulmonary embolism Safety Venous thromboembolism Vitamin K ePublished: 21 January 2014 Issue Published: 21 January 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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Available abstract

ACP Journal Club21 January 2014Edoxaban was noninferior to warfarin for preventing recurrent venous thromboembolism, with less bleedingStephan Thomé, MDStephan Thomé, MDMayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-160-2-201401210-02004 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail Source CitationHokusai-VTE Investigators. Edoxaban versus warfarin for the treatment of symptomatic venous thromboembolism. N Engl J Med. 2013;369:1406-15. https://pubmed.ncbi.nlm.nih.gov/23991658Clinical Impact RatingsGIM/FP/GP: Cardiology: Hematology: References1 Eikelboom JW, Connolly SJ, Brueckmann M, et al; RE-ALIGN Investigators. Dabigatran versus warfarin in patients with mechanical heart valves. N Engl J Med. 2013;369:1206-14. [PMID: 23991661] Google Scholar2 EINSTEIN Investigators, Bauersachs R, Berkowitz SD, et al. Oral rivaroxaban for symptomatic venous thromboembolism. N Eng J Med. 2010;363;2499-510. [PMID: 21128814] Google Scholar3 Agnelli G, Buller HR, Cohen A; AMPLIFY Investigators. Oral apixaban for the treatment of acute venous thromboembolism. N Eng J Med. 2013;369;799-808. [PMID: 23808982] Google Scholar Author, Article, and Disclosure InformationAuthors: Stephan Thomé, MDAffiliations: Mayo Clinic College of Medicine, Rochester, Minnesota, USA (S.T.)This article was published at Annals.org on 7 January 2014. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byIdentification of potential drug targets based on a computational biology algorithm for venous thromboembolism 21 January 2014Volume 160, Issue 2 Page: JC4 Keywords Cancer treatment Creatinine Deep vein thrombosis Hazard ratio Hemorrhage Heparin Pulmonary embolism Safety Venous thromboembolism Vitamin K ePublished: 21 January 2014 Issue Published: 21 January 2014 Copyright & PermissionsCopyright © 2014 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Key concepts: Medicine, Edoxaban, Rivaroxaban, Warfarin, Apixaban, Venous thromboembolism, Dabigatran, Pulmonary embolism

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