ScholarLens Back to search
2003•Journal of Cutaneous Medicine and SurgeryRequires access

Axillary Granular Parakeratosis

Joseph C. English, Amalie S. Derdeyn, Wendy M. Wilson, James W. Patterson

Open publisher page 13 citations

Abstract

BACKGROUND: Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. OBJECTIVE: The aim of the article is to review the clinical manifestations and treatment of granular parakeratosis. METHODS: A case report and literature review are presented. RESULTS: Twenty-six cases of granular parakeratosis now have been reported and reviewed. CONCLUSION: Granular parakeratosis occurs predominantly in middle age women and most frequently in the axilla. A number of treatments have been applied to the 26 cases reported to date, without consistent responses. No evidence-based therapy can be suggested at present.

About this research paper

What this paper is about

BACKGROUND: Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. OBJECTIVE: The aim of the article is to review the clinical manifestations and treatment of granular parakeratosis. METHODS: A case report and literature review are presented. RESULTS: Twenty-six cases of granular parakeratosis now have been reported and reviewed. CONCLUSION: Granular parakeratosis occurs predominantly in middle age women and most frequently in the axilla. A number of treatments have been applied to the 26 cases reported to date, without consistent responses. No evidence-based therapy can be suggested at present.

Why it matters

OpenAlex reports 13 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

BACKGROUND: Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. OBJECTIVE: The aim of the article is to review the clinical manifestations and treatment of granular parakeratosis. METHODS: A case report and literature review are presented. RESULTS: Twenty-six cases of granular parakeratosis now have been reported and reviewed. CONCLUSION: Granular parakeratosis occurs predominantly in middle age women and most frequently in the axilla. A number of treatments have been applied to the 26 cases reported to date, without consistent responses. No evidence-based therapy can be suggested at present.

Key concepts: Intertriginous, Parakeratosis, Medicine, Axilla, Dermatology, Stratum corneum, Etiology, Dyskeratosis

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Axillary Granular Parakeratosis — Research Paper | ScholarLens