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Mechanism of ‘bystander effect’ killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment

H Ishii-Morita, Riad Agbaria, CA Mullen, Hiroyuki Hirano, DA Koeplin, Zvi Ram, E H Oldfield, DG Johns, R. Michael Blaese

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Key concepts: Bystander effect, Thymidine kinase, Ganciclovir, Suicide gene, Biology, Cancer research, Genetic enhancement, Herpes simplex virus

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Mechanism of ‘bystander effect’ killing in the herpes simplex thymidine kinase gene therapy model of cancer treatment — Research Paper | ScholarLens