Depletion of Esterified Cholesterol in Mouse Testes and Leydig Cell Tumors by Luteinizing Hormone1
J. D. POKEL, William R. Moyle, ROY ORVAL GREEP
Abstract
J. D. POKEL, William R. Moyle, ROY ORVAL GREEP
Abstract
LH (50 μg) given sc to normal mice and Leydig cell tumor bearing mice promoted a decrease in the content of esterified cholesterol in the testes of normal mice and in the tumor. The observation that LH promoted a change in the tumor ester cholesterol levels was interpreted to mean that its action on testicular ester levels was probably on the interstitial cells. (Endocrinology91: 323, 1972
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LH (50 μg) given sc to normal mice and Leydig cell tumor bearing mice promoted a decrease in the content of esterified cholesterol in the testes of normal mice and in the tumor. The observation that LH promoted a change in the tumor ester cholesterol levels was interpreted to mean that its action on testicular ester levels was probably on the interstitial cells. (Endocrinology91: 323, 1972
Key concepts: Leydig cell, Endocrinology, Internal medicine, Leydig Cell Tumor, Cholesterol, Luteinizing hormone, Interstitial cell, Cell