2011•European Journal of Clinical PharmacologyRequires access

Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia

Dorababu Patchva, Narayana Nagesh, Vijay Gandhi Linga, Sadashivudu Gundeti, Vijay Kumar Kutala, Pallu Reddanna, Raghunadharao Digumarti

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Key concepts: ITPA, Thiopurine methyltransferase, Mercaptopurine, Biology, Genetics, Pharmacology, Genotype, Medicine

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Epistatic interactions between thiopurine methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) variations determine 6-mercaptopurine toxicity in Indian children with acute lymphoblastic leukemia — Research Paper | ScholarLens