2006•Bulletin of the Chemical Society of EthiopiaOpen access

3,7-DIDEACETYL-6α-HYDROXYKHIVORIN, A NEW LIMONOID FROM KHAYA SENEGALENSIS (MELIACEAE)

Pierre Tane, Michel K. Tchimene, Dieudonné Ngamga, Olov Sterner, Joseph D. Connolly

Abstract

A new limonoid, 3,7-dideacetyl-6α-hydroxykhivorin, together with khivorin, 3-deacetylkhivorin, 7-deacetoxy-3-deacetyl-7-oxokhivorin, and 6-deoxydestigloylswietenine acetate have been isolated from the seeds of Khaya senegalensis. Their structures were established by analysis of the high-field NMR and MS data. KEYWORDS: Khaya senegalensis, Limonoids, 3,7-Dideacetyl-6α-hydroxykhivorin, 7-Deacetoxy-3-deacetyl-7-oxokhivorin, 3-Deacetylkhivorin, 6-Deoxydestigloylswietenine acetate Bull. Chem. Soc. Ethiop. 2006, 20(1), 69-73.

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Key concepts: Limonoid, Khaya, Meliaceae, Chemistry, Traditional medicine, Stereochemistry, Medicine