1986Clinical and Experimental DermatologyRequires access

Failure of treatment of familial widespread hidradenitis suppurativa with isotretinoin

J.F.B. Norris, W.J. Cunliffe

Open publisher page 47 citations

Abstract

Isotretinoin has been used in the treatment of hidradenitis suppurativa with varying degrees of success. We investigated a family of six subjects with widespread hidradenitis suppurativa and treated them with isotretinoin at a dose of r mg kg for 4 months. No improvement was obtained and the subjects noted a flare in their disease activity alter stopping the drug. The rationale for treating hidradenitis suppurativa with isotretinoin is called into question.

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What this paper is about

Isotretinoin has been used in the treatment of hidradenitis suppurativa with varying degrees of success. We investigated a family of six subjects with widespread hidradenitis suppurativa and treated them with isotretinoin at a dose of r mg kg for 4 months. No improvement was obtained and the subjects noted a flare in their disease activity alter stopping the drug. The rationale for treating hidradenitis suppurativa with isotretinoin is called into question.

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Available abstract

Isotretinoin has been used in the treatment of hidradenitis suppurativa with varying degrees of success. We investigated a family of six subjects with widespread hidradenitis suppurativa and treated them with isotretinoin at a dose of r mg kg for 4 months. No improvement was obtained and the subjects noted a flare in their disease activity alter stopping the drug. The rationale for treating hidradenitis suppurativa with isotretinoin is called into question.

Key concepts: Hidradenitis suppurativa, Isotretinoin, Medicine, Dermatology, Disease, Acne, Internal medicine

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