2009•Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIERequires access

Photoacoustic monitoring of granulation tissue grown in grafted artificial dermis

Kousuke Hatanaka, Shunichi Sato, Daizoh Saitoh, Hiroshi Ashida, Toshihisa Sakamoto

Abstract

We investigated the validity of photoacoustic (PA) measurement for monitoring granulation tissue formed in the grafted artificial dermis (AD) in rats. We found that the depths of granulation tissue or neovascularities in the grafted AD can be monitored by PA measurement. There was a significant correlation between the PA signal amplitude and the density of neovascularities in the granulation tissue. These results suggest the usefulness of PA measurement for monitoring the adhesion of grafted ADs.

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Available abstract

Key concepts: Granulation tissue, Granulation, Photoacoustic imaging in biomedicine, Dermis, Materials science, Biomedical engineering, Adhesion, Composite material