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1974•Analytical LettersRequires access

Enzyme-Induced Chemiluminescence-Determination of Blood Glucose Using Luminol

Debra T. Bostick, David M. Hercules

Open publisher page 42 citations

Abstract

Hydrogen peroxide, produced by the interaction of glucose with immobilized glucose oxidase, reacts with the ferricyanide-luminol system to produce chemiluminescence linearly proportional to glucose concentration. The coupled reaction is used as a sensitive precise micro method for the determination of true blood glucose. The linear range of detection is 10−7 - 10−4 M glucose. The method correlates quantitatively with two glucose reference techniques.

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What this paper is about

Hydrogen peroxide, produced by the interaction of glucose with immobilized glucose oxidase, reacts with the ferricyanide-luminol system to produce chemiluminescence linearly proportional to glucose concentration. The coupled reaction is used as a sensitive precise micro method for the determination of true blood glucose. The linear range of detection is 10−7 - 10−4 M glucose. The method correlates quantitatively with two glucose reference techniques.

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OpenAlex reports 42 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Hydrogen peroxide, produced by the interaction of glucose with immobilized glucose oxidase, reacts with the ferricyanide-luminol system to produce chemiluminescence linearly proportional to glucose concentration. The coupled reaction is used as a sensitive precise micro method for the determination of true blood glucose. The linear range of detection is 10−7 - 10−4 M glucose. The method correlates quantitatively with two glucose reference techniques.

Key concepts: Chemistry, Chemiluminescence, Glucose oxidase, Luminol, Ferricyanide, Hydrogen peroxide, Chromatography, Linear range

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