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Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

Wilfried Dalemans, Pascal Barbry, Guy Champigny, Sophie Jallat, Sophie Jallat, Karin Dott, Dominique Dreyer, Ronald G. Crystal, Andréa Pavirani, Jean‐Pierre Lecocq, Michel Lazdunski

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Key concepts: Cystic fibrosis transmembrane conductance regulator, ΔF508, Chloride channel, Cystic fibrosis, Mutation, Chemistry, Heterologous expression, Molecular biology