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Mitochondria of adult human brown adipose tissue contain a 32 000-Mr uncoupling protein

Frédéric Bouillaud, M. Combes‐George, Daniel Ricquier

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Abstract

Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents.

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What this paper is about

Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents.

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OpenAlex reports 52 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Using both immunohistological study and photoaffinity labelling with radioactive azido-ATP, evidence is presented that the mitochondrial membranes of the brown adipose tissue of the human adult contain a 32 000-Mr uncoupling protein, which is probably similar to the uncoupling protein of BAT of rodents.

Key concepts: Brown adipose tissue, Uncoupling protein, Thermogenin, Mitochondrion, Adipose tissue, Labelling, Uncoupling Agents, Mitochondrial carrier

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