Disfunções cognitivas em pacientes com hipotireoidismo subclínico

OBJECTIVE: Evaluate neuropsychological changes in patients with subclinical hypothyroidism (SH). SUBJECTS AND METHODS: Cross-sectional study comparing the results of the neuropsychological evaluation of 89 SH patients and 178 individuals without thyroid disease. The participants underwent the following neuropsychological assessment: Conner's Continuous Performance Test (CPT-II), Iowa Gambling Task, Stroop Test, Wisconsin Card Sorting Test (WCST), Verbal Fluency Test (semantic and phonologic categories) and Rey Auditory Verbal Learning Test. RESULTS: Among the neuropsychological tests, patients showed worse performance only in cognitive flexibility (WCST) and the ability to maintain sustained attention (omission errors on the CPT-II). CONCLUSIONS: These losses can cause detriments in the daily lives of patients, constituting potential treatment indications.