John F. Hansen, Kazuyuki Kamata, Albert Irving Meyers
Abstract
Abstract A synthetic scheme leading to an isomeric DE ring (14) of the anti‐tumor alkaloid, camptothecin, has been achieved. However, the method failed to give the correct pyridone lactone (2) found in this alkaloid.
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Abstract A synthetic scheme leading to an isomeric DE ring (14) of the anti‐tumor alkaloid, camptothecin, has been achieved. However, the method failed to give the correct pyridone lactone (2) found in this alkaloid.
Key concepts: Camptothecin, Chemistry, Alkaloid, Ring (chemistry), Lactone, Stereochemistry, Combinatorial chemistry, Organic chemistry