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1973•Journal of Paediatrics and Child HealthRequires access

A FAMILY STUDY OF COELIAC DISEASE

Astrid Gardiner, Kenneth J. Mutton, J A Walker‐Smith

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Abstract

This is a study of the families of 50 children with coeliac disease. A number of genetic and acquired factors of possible importance in the etiology of coeliac disease were observed. 2 siblings were found to have biopsy-proven coeliac disease and in 3 mothers a clinical diagnosis of coeliac disease had been made, i.e. in 5 (2.4%) of 210 first degree relatives a diagnosis of coeliac disease had been made. The mean age of introduction of gluten into the diet was identical (3.2 months) for both the coeliac children and their non-coeliac siblings.

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What this paper is about

This is a study of the families of 50 children with coeliac disease. A number of genetic and acquired factors of possible importance in the etiology of coeliac disease were observed. 2 siblings were found to have biopsy-proven coeliac disease and in 3 mothers a clinical diagnosis of coeliac disease had been made, i.e. in 5 (2.4%) of 210 first degree relatives a diagnosis of coeliac disease had been made. The mean age of introduction of gluten into the diet was identical (3.2 months) for both the coeliac children and their non-coeliac siblings.

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OpenAlex reports 14 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This is a study of the families of 50 children with coeliac disease. A number of genetic and acquired factors of possible importance in the etiology of coeliac disease were observed. 2 siblings were found to have biopsy-proven coeliac disease and in 3 mothers a clinical diagnosis of coeliac disease had been made, i.e. in 5 (2.4%) of 210 first degree relatives a diagnosis of coeliac disease had been made. The mean age of introduction of gluten into the diet was identical (3.2 months) for both the coeliac children and their non-coeliac siblings.

Key concepts: Coeliac disease, Medicine, Etiology, Gluten, Disease, Biopsy, Pediatrics, Gastroenterology

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