A new phenolic glycoside from the stems of Clematis parviloba

A new phenolic glycoside, clemaparviloside A ( 1 ) together with three known megastigmane glycosides, linarionoside A ( 2 ), linarionoside C ( 3 ) and staphylionoside K ( 4 ) were isolated from the stems of Clematis parviloba [1,2]. Their structures were determined on the basis of spectroscopic analysis and chemical evidence. The megastigmane glycoside compounds are reported for the first time to be obtained from Clematis genus. In addition, compound 1 was examined its inhibitory activity against murine fibrosarcoma L929 cells in vitro . References: [1] Hideaki, O. (1994) Phytochemistry 37:461–465. [2] Qian, Y. et al. (2005) Chem. Pharm. Bull. 53:800–807.