2010•Journal of Pediatric Hematology/OncologyRequires access

Anaphylactic Reaction Owing to Ondansetron Administration in a Child With Neuroblastoma and Safe Use of Granisetron: A Case Report

Hacı Ahmet Demir, Ezgi Deniz Batu, Bilgehan Yalçın, Ersoy Civelek, Cansın Saçkesen, Münevver Büyükpamukçu

Abstract

A 1-year-old girl with stage-IV neuroblastoma developed ondansetron hydrochloride anaphylaxis. Safe use of granisetron as an antiemetic after skin prick, oral, and intravenous challenge tests is presented. We present this case to emphasize that ondansetron hydrochloride may cause a serious anaphylactic reaction. In such a case, granisetron may be given to patients as an antiemetic after some provocative tests performed.

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Key concepts: Ondansetron, Medicine, Granisetron, Antiemetic, Anesthesia, Anaphylaxis, Neuroblastoma, Nausea