1964Archives of OphthalmologyRequires access

Melanocytoma of the Ciliary Body

J. F. BOWERS

Open publisher page 35 citations

Abstract

Zimmerman1presented evidence of a locally invasive, nonmalignant, primary melanotic tumor of the optic disc which arose from normal uveal melanocytes. This tumor was benign, over half of the reported cases were in Negroes, and it offered an excellent prognosis. The distinctive namemelanocytomawas used to differentiate this tumor from choroidal melanomas which involved the nerve head. Over 30 melanocytomas of the optic disc have been reported. There have been no reports of metastasis, but the tumors have been found to be locally invasive, infiltrating posterior to the lamina cribrosa and into the adjacent choroid. The most important distinguishing feature of this tumor is its benign clinical course which is characterized by slow growth and rare decrease in the patient's visual acuity. These observations have made it clear that enucleation is not necessary. Cytologically the cells are remarkably uniform and heavily laden with pigment granules which appear morphologically

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What this paper is about

Zimmerman1presented evidence of a locally invasive, nonmalignant, primary melanotic tumor of the optic disc which arose from normal uveal melanocytes. This tumor was benign, over half of the reported cases were in Negroes, and it offered an excellent prognosis. The distinctive namemelanocytomawas used to differentiate this tumor from choroidal melanomas which involved the nerve head. Over 30 melanocytomas of the optic disc have been reported. There have been no reports of metastasis, but the tumors have been found to be locally invasive, infiltrating posterior to the lamina cribrosa and into the adjacent choroid. The most important distinguishing feature of this tumor is its benign clinical course which is characterized by slow growth and rare decrease in the patient's visual acuity. These observations have made it clear that enucleation is not necessary. Cytologically the cells are remarkably uniform and heavily laden with pigment granules which appear morphologically

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Available abstract

Zimmerman1presented evidence of a locally invasive, nonmalignant, primary melanotic tumor of the optic disc which arose from normal uveal melanocytes. This tumor was benign, over half of the reported cases were in Negroes, and it offered an excellent prognosis. The distinctive namemelanocytomawas used to differentiate this tumor from choroidal melanomas which involved the nerve head. Over 30 melanocytomas of the optic disc have been reported. There have been no reports of metastasis, but the tumors have been found to be locally invasive, infiltrating posterior to the lamina cribrosa and into the adjacent choroid. The most important distinguishing feature of this tumor is its benign clinical course which is characterized by slow growth and rare decrease in the patient's visual acuity. These observations have made it clear that enucleation is not necessary. Cytologically the cells are remarkably uniform and heavily laden with pigment granules which appear morphologically

Key concepts: Melanocytoma, Ciliary body, Medicine, Ophthalmology, Melanoma, Cancer research

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