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1958•Journal of Pharmacy and PharmacologyRequires access

THE MECHANISM OF HISTAMINE LIBERATION

Börje Uvnäs

Open publisher page 56 citations

Abstract

Abstract Theories have to be modified from time to time as fresh experimental data emerge. Recent years have brought new observations as to the localisation and the chemical binding of histamine in the tissues. Synthetic and biologically occurring histamine liberators constitute a new group of more or less specific substances and compounds, the histamine releasing properties of which were, until only a few years ago, completely unknown. The data available today necessitate reconsideration of the validity of existing theories on the mechanism of histamine liberation.

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What this paper is about

Abstract Theories have to be modified from time to time as fresh experimental data emerge. Recent years have brought new observations as to the localisation and the chemical binding of histamine in the tissues. Synthetic and biologically occurring histamine liberators constitute a new group of more or less specific substances and compounds, the histamine releasing properties of which were, until only a few years ago, completely unknown. The data available today necessitate reconsideration of the validity of existing theories on the mechanism of histamine liberation.

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Available abstract

Abstract Theories have to be modified from time to time as fresh experimental data emerge. Recent years have brought new observations as to the localisation and the chemical binding of histamine in the tissues. Synthetic and biologically occurring histamine liberators constitute a new group of more or less specific substances and compounds, the histamine releasing properties of which were, until only a few years ago, completely unknown. The data available today necessitate reconsideration of the validity of existing theories on the mechanism of histamine liberation.

Key concepts: Histamine, Liberation, Mechanism (biology), Chemistry, Pharmacology, Medicine, Biochemistry, Philosophy

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