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Effects of cordacin on lymphocyte activity in vitro.

Chen Jy, Deng Js, Lin Yc

Abstract

The effects of cordacin on lymphocyte activity were studied with two parameters in vitro. The cordacin inhibited T lymphocyte E rosette formation by 93% at the concentration of 1,000 microgram/ml and tritiated-thymidine incorporation into PHA-transformed lymphocytes by 66% at the concentration of 10 microgram/ml. The implication of these results on replicating leukemic as well as normal cells is discussed.

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Available abstract

Key concepts: Microgram, In vitro, Thymidine, Lymphocyte, Rosette formation, Chemistry, Lymphocyte activation, Molecular biology