2007•The Pediatric Infectious Disease JournalRequires access
Epidemiology and Clinical Presentation of Shigellosis in Children Less Than Five Years of Age in Rural Mozambique
Inácio Mandomando, Betuel Sigaúque, Xavier Vallès, Mateu Espasa, Sergi Sanz, Jahit Sacarlal, Eusébio Macete, Fátima Abacassamo, Joaquı́m Ruiz, Joaquím Gascón, Karen L. Kotloff, Myron M. Levine, Pedro L. Alonso
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Abstract
Rectal swabs were collected from 1354 children <5 years of age with diarrhea attending Manhiça District Hospital and from 227 healthy community controls. Shigellosis incidence was high among children aged 12-47 months (488.4/10(5) child-years at risk). Fever and dysentery were prominent clinical findings. Shigella was more frequently isolated from cases than controls (6.7% versus 0.4%, P = 0.004), and from dysentery than nondysenteric diarrhea (24.1% versus 3.5%, P < 0.001). Shigella flexneri 2a, S. sonnei, and S. flexneri 6, were the most prevalent serotypes.