Histamine Degradation in Tissue Extracts from the Cat
Kerstin M. Lindahl, S.‐E. Lindell, H. Westling, Tonya J.H. White
Abstract
Kerstin M. Lindahl, S.‐E. Lindell, H. Westling, Tonya J.H. White
Abstract
Summary. 1. The degradation of added histamine by crude extracts of kidney and small intestinal mucosa from adult cats was studied by measuring the oxygen consumption manometrically and by observing the loss of biological activity. 2. It was found that these extracts contained a histamine degradating enzyme with the characteristics of diamine oxidase. 3. No conclusive evidence was found in these experiments for the action of a histamine inactivating enzyme other than diamine oxidase.
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Summary. 1. The degradation of added histamine by crude extracts of kidney and small intestinal mucosa from adult cats was studied by measuring the oxygen consumption manometrically and by observing the loss of biological activity. 2. It was found that these extracts contained a histamine degradating enzyme with the characteristics of diamine oxidase. 3. No conclusive evidence was found in these experiments for the action of a histamine inactivating enzyme other than diamine oxidase.
Key concepts: Diamine oxidase, Histamine, CATS, Chemistry, Amine oxidase (copper-containing), Enzyme, Degradation (telecommunications), Histamine N-methyltransferase