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Gamma Knife Thalamotomy and Pallidotomy in Patients with Movement Disorders: Preliminary Results

Robert W. Rand, David Jacques, R.W. Melbye, Brian Copcutt, M.R. Fisher, M.N. Levenick

Open publisher page 59 citations

Abstract

The Leksell Gamma Knife is a useful and safe method to perform thalamotomy and pallidotomy in selected older patients with Parkinson's disease and related movement disorders. In this preliminary report, 2 of 3 patients with severe intention tremor were relieved of their symptoms by thalamotomy, as were 4 of 7 patients with Parkinson's tremor. Four of 8 patients had significant improvement of contralateral rigidity following pallidotomy.

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What this paper is about

The Leksell Gamma Knife is a useful and safe method to perform thalamotomy and pallidotomy in selected older patients with Parkinson's disease and related movement disorders. In this preliminary report, 2 of 3 patients with severe intention tremor were relieved of their symptoms by thalamotomy, as were 4 of 7 patients with Parkinson's tremor. Four of 8 patients had significant improvement of contralateral rigidity following pallidotomy.

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OpenAlex reports 59 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The Leksell Gamma Knife is a useful and safe method to perform thalamotomy and pallidotomy in selected older patients with Parkinson's disease and related movement disorders. In this preliminary report, 2 of 3 patients with severe intention tremor were relieved of their symptoms by thalamotomy, as were 4 of 7 patients with Parkinson's tremor. Four of 8 patients had significant improvement of contralateral rigidity following pallidotomy.

Key concepts: Thalamotomy, Pallidotomy, Medicine, Movement disorders, Parkinson's disease, Essential tremor, Physical medicine and rehabilitation, Stereotactic surgery

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