ScholarLens Back to search
1972•Journal of EndocrinologyRequires access

A SOLID PHASE RADIOIMMUNOASSAY FOR OVINE AND CAPRINE PROLACTIN USING SEPHAROSE 6B: ITS APPLICATION TO THE MEASUREMENT OF CIRCULATING LEVELS OF PROLACTIN BEFORE AND DURING PARTURITION IN THE GOAT

I. C. Hart

Open publisher page 35 citations

Abstract

SUMMARY A rapid solid phase radioimmunoassay for ovine and caprine prolactin is described utilizing antibodies chemically bound to Sepharose 6B. Prolactin was measured in blood samples taken from goats at varying intervals before the onset of the first stage of labour. The concentration of prolactin rose 5–35 h before parturition to a level 2·6–4·5 times the lowest concentration found earlier in gestation. The results of serial samples taken during the first and second stages of labour indicate that the intense uterine contractions associated with the expulsion of the kid are associated with a large increase in the level of prolactin in the blood.

About this research paper

What this paper is about

SUMMARY A rapid solid phase radioimmunoassay for ovine and caprine prolactin is described utilizing antibodies chemically bound to Sepharose 6B. Prolactin was measured in blood samples taken from goats at varying intervals before the onset of the first stage of labour. The concentration of prolactin rose 5–35 h before parturition to a level 2·6–4·5 times the lowest concentration found earlier in gestation. The results of serial samples taken during the first and second stages of labour indicate that the intense uterine contractions associated with the expulsion of the kid are associated with a large increase in the level of prolactin in the blood.

Why it matters

OpenAlex reports 35 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

SUMMARY A rapid solid phase radioimmunoassay for ovine and caprine prolactin is described utilizing antibodies chemically bound to Sepharose 6B. Prolactin was measured in blood samples taken from goats at varying intervals before the onset of the first stage of labour. The concentration of prolactin rose 5–35 h before parturition to a level 2·6–4·5 times the lowest concentration found earlier in gestation. The results of serial samples taken during the first and second stages of labour indicate that the intense uterine contractions associated with the expulsion of the kid are associated with a large increase in the level of prolactin in the blood.

Key concepts: Radioimmunoassay, Prolactin, Endocrinology, Internal medicine, Gestation, Chemistry, Sepharose, Antibody

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
A SOLID PHASE RADIOIMMUNOASSAY FOR OVINE AND CAPRINE PROLACTIN USING SEPHAROSE 6B: ITS APPLICATION TO THE MEASUREMENT OF CIRCULATING LEVELS OF PROLACTIN BEFORE AND DURING PARTURITION IN THE GOAT — Research Paper | ScholarLens