P78Second trimester uterine artery Doppler velocimetry in the prediction of poor perinatal outcome

Background The patients with an increase of resistance of uterine arteries in second trimester has between 5 and 8 times increased the risk of presenting adverse perinatal outcome. The objective is to evaluate the utility of uterine artery Doppler velocimetry in the prediction of poor perinatal outcome. Method We performed a prospective study, in 512 consecutives pregnant women between 22 and 24 +6 weeks of pregnancy. Uterine artery Doppler velocimetry was done in all patients using color Doppler duplex technique. The presence of notch or resistance index over 95 centile was defined as abnormal. Adverse perinatal outcome was defined as presence of preeclampsia, intrauterine growth retardation, and preterm delivery before 34 weeks of pregnancy. For statistical analysis non parametrics test and meta analisis model was used. Results Uterine artery Doppler velocimetry was carried out in 512 patients, 198 was delivered. Resistance index was significantly higher in poor perinatal outcome group than in normal perinatal outcome group (Pulsatility index 1.38 vs. 0.9; P < 0.001). The relative risk of presenting adverse perinatal outcome was 3.8 times higher in patients with abnormal uterine artery Doppler velocimetry compared with those that has normal uterine artery Doppler velocimetry (ic 95%; 1.8–7.7; P < 0.0006). Conclusion. Uterine artery Doppler velocimetry evaluated in the second trimester of pregnancy is able to identify high risk patients of poor perinatal outcome.