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1975•Scandinavian Journal of ImmunologyRequires access

Production of Antiserum against a Specific Herpes Simplex Virus Type 2 Antigen

Bent Faber Vestergaard

Open publisher page 38 citations

Abstract

Antisera were produced in rabbits by inoculation of precipitates cut out of second dimensional agarose gels from crossed immunoelectrophoreses. The precipitating antigen chosen (antigen no. 1) had previously been identified as specific for herpes simplex virus type 2. Crossed immunoelectrophoretic analysis of the produced antisera revealed that the antisera contained a high concentration of precipitating antibodies that reacted exclusively with antigen no. 1 and a minor antigen with the same electrophoretic mobility. The produced antisera were useful in the typing of herpes simplex virus isolates by rocket immunoelectrophoresis.

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What this paper is about

Antisera were produced in rabbits by inoculation of precipitates cut out of second dimensional agarose gels from crossed immunoelectrophoreses. The precipitating antigen chosen (antigen no. 1) had previously been identified as specific for herpes simplex virus type 2. Crossed immunoelectrophoretic analysis of the produced antisera revealed that the antisera contained a high concentration of precipitating antibodies that reacted exclusively with antigen no. 1 and a minor antigen with the same electrophoretic mobility. The produced antisera were useful in the typing of herpes simplex virus isolates by rocket immunoelectrophoresis.

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OpenAlex reports 38 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

Antisera were produced in rabbits by inoculation of precipitates cut out of second dimensional agarose gels from crossed immunoelectrophoreses. The precipitating antigen chosen (antigen no. 1) had previously been identified as specific for herpes simplex virus type 2. Crossed immunoelectrophoretic analysis of the produced antisera revealed that the antisera contained a high concentration of precipitating antibodies that reacted exclusively with antigen no. 1 and a minor antigen with the same electrophoretic mobility. The produced antisera were useful in the typing of herpes simplex virus isolates by rocket immunoelectrophoresis.

Key concepts: Antiserum, Antigen, Immunoelectrophoresis, Virology, Herpes simplex virus, Biology, Agarose, Virus

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