2000•Molecular CellRequires access

Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice

Iichiro Shimomura, Morihiro Matsuda, Robert E. Hammer, Yuriy K. Bashmakov, M S Brown, Joseph L. Goldstein

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Key concepts: Internal medicine, Hyperinsulinemia, Endocrinology, Insulin resistance, Biology, Lipogenesis, Insulin, Leptin

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Decreased IRS-2 and Increased SREBP-1c Lead to Mixed Insulin Resistance and Sensitivity in Livers of Lipodystrophic and ob/ob Mice — Research Paper | ScholarLens