Patrick T. Gunning
Abstract
The synthesis of a heteroditopic receptor which exhibits positive cooperativity for the binding of phosphate ion pairs under physiological conditions. Optimised complementarity between crown ether host and metal guest leads to increased binding affinity, Ka.
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The synthesis of a heteroditopic receptor which exhibits positive cooperativity for the binding of phosphate ion pairs under physiological conditions. Optimised complementarity between crown ether host and metal guest leads to increased binding affinity, Ka.
Key concepts: Cooperativity, Chemistry, Cooperative binding, Phosphate, Ion, Complementarity (molecular biology), Crown ether, Binding site