Studies of Antimicrobial Activity of two Synthetic 2`, 4`, 6`-trioxygenated Flavones

Two 2N, 4N, 6N-trioxygenated flavones has been synthesized and tested for antibacterial and antifungal activities along with their corresponding chalcones against four human pathogenic bacteria and five plant as well as molds fungi. UV, IR and H NMMR techniques together with elemental analysis elucidated the 1 structures of the synthesized compounds. The antibacterial and antifungal screen was performed in vitro by the filter paper disc diffusion method and poisoned food technique. Compound 6 and 7 showed antibacterial activity but their corresponding chalcones didn’t show any activity against tested bacteria. Compound 4 and its corresponding chalcone 6 didn’t show any antifungal activity where as compound 5 and its flavone 7 showed moderate antifungal activity against Penicillium sp and Colletorichum gloeosporioides.