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Enteric Film Coating Using Completely Aqueous Dissolved Hydroxypropyl Methyl Cellulose Phthalate Spray Solutions

John W. Stafford, Sandoz Ag

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Abstract

A completely aqueous film coating spray system has been developed for the enteric film coating of tablets. The method uses conventional aqueous film coating equipment and techniques. The coatings produced compare in enteric quality with the best that can be achieved with enteric film coatings applied from organic solutions. Dissolution rate data were mainly used to judge the enteric quality, and such data for a number of enteric film coating trials are presented.

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What this paper is about

A completely aqueous film coating spray system has been developed for the enteric film coating of tablets. The method uses conventional aqueous film coating equipment and techniques. The coatings produced compare in enteric quality with the best that can be achieved with enteric film coatings applied from organic solutions. Dissolution rate data were mainly used to judge the enteric quality, and such data for a number of enteric film coating trials are presented.

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OpenAlex reports 23 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

A completely aqueous film coating spray system has been developed for the enteric film coating of tablets. The method uses conventional aqueous film coating equipment and techniques. The coatings produced compare in enteric quality with the best that can be achieved with enteric film coatings applied from organic solutions. Dissolution rate data were mainly used to judge the enteric quality, and such data for a number of enteric film coating trials are presented.

Key concepts: Enteric coating, Coating, Enteric coated, Aqueous solution, Dissolution, Film coating, Materials science, Hydroxypropyl cellulose

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