2005•NeurologyRequires access
Evidence for superior parietal impairment in Williams syndrome
Mark A. Eckert, Diane Hu, Stéphan Eliez, Ursula Bellugi, Albert M. Galaburda, Julie R. Korenberg, Debra L. Mills, Allan L. Reiss
Open publisher page 113 citations
Abstract
Parietal lobe impairment is hypothesized to contribute to the dramatic visual-spatial deficits in Williams syndrome (WS). The authors examined the superior and inferior parietal lobule in 17 patients with WS and 17 control female adults (CNLs). The right and left superior parietal lobule gray matter volumes were significantly smaller in patients with WS than in CNLs, even after controlling for total cerebral gray matter. Impaired superior parietal function could explain WS visual-spatial and visual-motor problems.