2008•European Surgical ResearchRequires access

Graft-versus-Host Reaction Induced by Spleen Grafting in Inbred Strains of Rats

Jean Gugenheim, D Houssin, Eléonora De Martin, Henri Bismuth

Abstract

Acute graft-versus-host (GvH) reaction was induced by spleen grafting in inbred rats. A comparison of the influence of portal or caval drainage of the spleen graft on the survival time was made. This comparison revealed a prolongation of survival time in case of a portal drainage when the graft was an auxiliary half-spleen graft. This result suggests that the liver may have, in some conditions, protective capacities against an acute GvH reaction.

About this research paper

What this paper is about

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Spleen, Graft vs Host Reaction, Grafting, Medicine, Surgery, Biology, Immunology, Transplantation