1987•Journal of Heterocyclic ChemistryRequires access

Synthesis and antifungal activity of some allylamine derivatives

Tiziano Bandiera, Franca Marinone Albini, E Albini

Abstract

Abstract Benzo‐ and mesitonitrile oxides react with allylamine to yield 5‐aminomethyl‐2‐isoxazolines and open‐chain N ‐substituted amidoximes. The allylamine derivatives were evaluated as potential antifungal and antibacterial agents. The N ‐allylbenzamidoxime 2a was found to be only moderately active against dermatophytes.

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Key concepts: Allylamine, Chemistry, Antifungal, Yield (engineering), Organic chemistry, Microbiology, Polymer, Materials science