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2008•Bioorganic & Medicinal ChemistryRequires access

New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (±)-cromakalim as tissue-selective pancreatic β-cell KATP channel openers

S. Sebille, Pascal De Tullio, Xavier Florence, Bénédicte Becker, M. H. Antoine, Catherine Michaux, Johan Wouters, Bernard Pirotte, Philippe Lebrun

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Key concepts: Cromakalim, Pinacidil, Chemistry, Benzopyrans, Diazoxide, Potassium channel, Benzopyran, Potassium channel opener

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New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (±)-cromakalim as tissue-selective pancreatic β-cell KATP channel openers — Research Paper | ScholarLens