Coenzyme A Changes in Liver, Spleen and Kidney of Rats with Infections of Plasmodium berghei
Irwin Singer, W. Trager
Abstract
Irwin Singer, W. Trager
Abstract
Co A concentration and total content in liver, spleen, and kidney of normal rats and rats with infections of Plasmodium berghei have been described. During the course of infection the concentration of Co A in the liver dropped but the total amount present was unchanged. In the spleen the concentration remained static, whereas the total was proportional to the increased size of the organ. The kidney showed no appreciable changes in Co A, but a decreased concentration of free pantothenate was apparent in young infected animals.
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Co A concentration and total content in liver, spleen, and kidney of normal rats and rats with infections of Plasmodium berghei have been described. During the course of infection the concentration of Co A in the liver dropped but the total amount present was unchanged. In the spleen the concentration remained static, whereas the total was proportional to the increased size of the organ. The kidney showed no appreciable changes in Co A, but a decreased concentration of free pantothenate was apparent in young infected animals.
Key concepts: Plasmodium berghei, Spleen, Kidney, Malaria, Internal medicine, Endocrinology, Biology, Chemistry