1956Experimental Biology and MedicineRequires access

Coenzyme A Changes in Liver, Spleen and Kidney of Rats with Infections of Plasmodium berghei

Irwin Singer, W. Trager

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Abstract

Co A concentration and total content in liver, spleen, and kidney of normal rats and rats with infections of Plasmodium berghei have been described. During the course of infection the concentration of Co A in the liver dropped but the total amount present was unchanged. In the spleen the concentration remained static, whereas the total was proportional to the increased size of the organ. The kidney showed no appreciable changes in Co A, but a decreased concentration of free pantothenate was apparent in young infected animals.

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What this paper is about

Co A concentration and total content in liver, spleen, and kidney of normal rats and rats with infections of Plasmodium berghei have been described. During the course of infection the concentration of Co A in the liver dropped but the total amount present was unchanged. In the spleen the concentration remained static, whereas the total was proportional to the increased size of the organ. The kidney showed no appreciable changes in Co A, but a decreased concentration of free pantothenate was apparent in young infected animals.

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Available abstract

Co A concentration and total content in liver, spleen, and kidney of normal rats and rats with infections of Plasmodium berghei have been described. During the course of infection the concentration of Co A in the liver dropped but the total amount present was unchanged. In the spleen the concentration remained static, whereas the total was proportional to the increased size of the organ. The kidney showed no appreciable changes in Co A, but a decreased concentration of free pantothenate was apparent in young infected animals.

Key concepts: Plasmodium berghei, Spleen, Kidney, Malaria, Internal medicine, Endocrinology, Biology, Chemistry

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Coenzyme A Changes in Liver, Spleen and Kidney of Rats with Infections of Plasmodium berghei — Research Paper | ScholarLens