Ralph Carmel, Yash Pal Agrawal
Abstract
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The authors show that commercial tests for cobalamin levels provide false normal values in 22 to 35% of cases of pernicious anemia, the main disease they were designed to detect. The manufacturers need to solve the problem of interference of the assay by antibodies to intrinsic factor.
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The authors show that commercial tests for cobalamin levels provide false normal values in 22 to 35% of cases of pernicious anemia, the main disease they were designed to detect. The manufacturers need to solve the problem of interference of the assay by antibodies to intrinsic factor.
Key concepts: Cobalamin, pernicious anemia, Medicine, Intrinsic factor, Anemia, Pernicious anaemia, Vitamin B12, Physiology