1986Antimicrobial Agents and ChemotherapyOpen access

Ciprofloxacin therapy for Mediterranean spotted fever

Didier Raoult, H Gallais, P. De Micco, Paul Casanova

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Abstract

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

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What this paper is about

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

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Available abstract

We report the treatment of five patients with Mediterranean spotted fever with the antimicrobial agent ciprofloxacin. The treatment was administered intravenously for 2 days and then perorally for 8 days. All five patients were cured. These preliminary data seem to correlate with the in vitro activity of ciprofloxacin against Rickettsia conorii.

Key concepts: Rickettsia conorii, Ciprofloxacin, Spotted fever, Boutonneuse fever, Antimicrobial, Rickettsiosis, Antibiotics, Microbiology

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